{"id":1703,"date":"2021-11-16T08:07:14","date_gmt":"2021-11-16T08:07:14","guid":{"rendered":"https:\/\/www.junshipharma.com\/?p=1703"},"modified":"2023-01-12T08:09:51","modified_gmt":"2023-01-12T08:09:51","slug":"%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%97%e6%b2%bb%e7%96%97%e9%a3%9f%e7%ae%a1%e7%99%8c%e8%8e%b7%e5%be%97%e7%be%8e%e5%9b%bdfda%e5%ad%a4%e5%84%bf","status":"publish","type":"post","link":"https:\/\/www.junshipharma.com\/%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%97%e6%b2%bb%e7%96%97%e9%a3%9f%e7%ae%a1%e7%99%8c%e8%8e%b7%e5%be%97%e7%be%8e%e5%9b%bdfda%e5%ad%a4%e5%84%bf\/","title":{"rendered":"\u541b\u5b9e\u751f\u7269\u7279\u745e\u666e\u5229\u5355\u6297\u6cbb\u7597\u98df\u7ba1\u764c\u83b7\u5f97\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a"},"content":{"rendered":"\n<p>\u5317\u4eac\u65f6\u95f42021\u5e7411\u670815\u65e5\uff0c\u541b\u5b9e\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u5ba3\u5e03\uff0c\u7531\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u6297PD-1\u5355\u6297\u836f\u7269\u7279\u745e\u666e\u5229\u5355\u6297\u7528\u4e8e\u6cbb\u7597\u98df\u7ba1\u764c\uff08EC\uff09\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88\u7684\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff08Orphan-drug 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id=\"_ftnref2\" href=\"#_ftn2\"><sup>[2]<\/sup><\/a><a id=\"_ftnref3\" href=\"#_ftn3\"><sup>[3]<\/sup><\/a>\u3002\u6839\u636e\u7f8e\u56fd\u764c\u75c7\u534f\u4f1a\u7edf\u8ba1\uff0c2021\u5e74\u7f8e\u56fd\u9884\u8ba1\u7ea6\u6709\u98df\u7ba1\u764c\u65b0\u53d1\u75c5\u4f8b19,000\u4f8b\u53ca\u6b7b\u4ea1\u75c5\u4f8b15,000\u4f8b<sup>[4]<\/sup>\u3002\u665a\u671f\u98df\u7ba1\u764c\u60a3\u8005\u7684\u9884\u540e\u8f83\u5dee\uff0c\u4ee5\u94c2\u7c7b\u4e3a\u57fa\u7840\u7684\u4e00\u7ebf\u5316\u7597\u65b9\u6848\uff0c5\u5e74\u603b\u751f\u5b58\u7387\u4ecd\u5c0f\u4e8e20%<sup>[5]<\/sup>\u3002<\/p>\n\n\n\n<p>\u76ee\u524d\uff0c\u541b\u5b9e\u751f\u7269\u9488\u5bf9\u98df\u7ba1\u764c\u5f00\u5c55\u4e862\u9879\u7279\u745e\u666e\u5229\u5355\u6297\u7684III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\u3002\u5176\u4e2d\uff0cJUPITER-06\u7814\u7a76\uff08NCT03829969\uff09\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3\u7684III\u671f\u7814\u7a76\uff0c\u65e8\u5728\u6bd4\u8f83\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u7d2b\u6749\u9187\/\u987a\u94c2\uff08TP\u5316\u7597\uff09\u4e0e\u5b89\u6170\u5242\u8054\u5408TP\u5316\u7597\u5728\u665a\u671f\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u4e00\u7ebf\u6cbb\u7597\u4e2d\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u30022021\u5e749\u6708\uff0cJUPITER-06\u7814\u7a76\u57282021\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5e74\u4f1a\u9996\u6b21\u516c\u5e03\u7ed3\u679c\uff08<a href=\"https:\/\/mp.weixin.qq.com\/s\/vhotXWoCwkvZb15FTryAgg\"><em>\u76f8\u5173\u9605\u8bfb<\/em><\/a>\uff09\u3002\u8be5\u7814\u7a76\u8fbe\u5230\u4e86\u590d\u5408\u4e3b\u8981\u7ec8\u70b9\uff0c\u4e0e\u5355\u7eaf\u5316\u7597\u76f8\u6bd4\uff0c\u63a5\u53d7\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u6cbb\u7597\u7684\u60a3\u8005\u5728\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u603b\u751f\u5b58\u671f\uff08OS\uff09\u65b9\u9762\u5747\u83b7\u5f97\u4e86\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\u548c\u4e34\u5e8a\u610f\u4e49\u7684\u663e\u8457\u6539\u5584\u3002\u57fa\u4e8eJUPITER-06\u7814\u7a76\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u4e8e2021\u5e747\u6708\u53d7\u7406\u4e86\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u542b\u94c2\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\uff08<a href=\"https:\/\/mp.weixin.qq.com\/s\/MdYIZZQLqN5LLWITOLRJ4A\"><em>\u76f8\u5173\u9605\u8bfb<\/em><\/a>\uff09\u3002\u541b\u5b9e\u751f\u7269\u4e5f\u8ba1\u5212\u4e0e\u6d77\u5916\u5408\u4f5c\u4f19\u4f34Coherus\u4e8e2022\u5e74\u5411\u7f8e\u56fdFDA\u63d0\u4ea4\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u542b\u94c2\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u665a\u671f\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u9002\u5e94\u75c7\u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\u3002<\/p>\n\n\n\n<p>\u6b64\u5916\uff0c\u4e00\u9879\u56f4\u624b\u672f\u671f\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u65b0\u8f85\u52a9\u5316\u7597\u6cbb\u7597\u53ef\u5207\u9664\u5c40\u90e8\u665a\u671f\u80f8\u6bb5\u98df\u7ba1\u9cde\u764c\u7684\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff08NCT04848753\uff09\u6b63\u5728\u5f00\u5c55\u4e2d\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e\uff1a<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\"><a id=\"_ftn1\" href=\"#_ftnref1\">[1]<\/a> https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/6-Oesophagus-fact-sheet.pdf<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\"><a href=\"#_ftnref2\" id=\"_ftn2\">[2]<\/a> https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/6-Oesophagus-fact-sheet.pdf<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\"><a href=\"#_ftnref3\" id=\"_ftn3\">[3]<\/a> https:\/\/gco.iarc.fr\/today\/data\/factsheets\/populations\/160-china-fact-sheets.pdf<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\"><a href=\"#_ftnref4\" id=\"_ftn4\">[4]<\/a> https:\/\/www.cancer.org\/cancer\/esophagus-cancer\/about\/key-statistics.html<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\"><a id=\"_ftn5\" href=\"#_ftnref5\">[5]<\/a> 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