{"id":2139,"date":"2023-04-21T10:53:22","date_gmt":"2023-04-21T10:53:22","guid":{"rendered":"https:\/\/www.junshipharma.com\/?p=2139"},"modified":"2023-05-04T10:37:18","modified_gmt":"2023-05-04T10:37:18","slug":"%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e9%a6%96%e6%ac%a1%e5%85%ac%e5%b8%83%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%97%e5%9b%b4%e6%89%8b%e6%9c%af%e6%9c%9f%e6%b2%bb%e7%96%97%e9%9d%9e%e5%b0%8f","status":"publish","type":"post","link":"https:\/\/www.junshipharma.com\/%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e9%a6%96%e6%ac%a1%e5%85%ac%e5%b8%83%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%97%e5%9b%b4%e6%89%8b%e6%9c%af%e6%9c%9f%e6%b2%bb%e7%96%97%e9%9d%9e%e5%b0%8f\/","title":{"rendered":"\u541b\u5b9e\u751f\u7269\u9996\u6b21\u516c\u5e03\u7279\u745e\u666e\u5229\u5355\u6297\u56f4\u624b\u672f\u671f\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u4e09\u671f\u7814\u7a76\u6570\u636e\uff0c\u75be\u75c5\u590d\u53d1\u3001\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u8fbe60%"},"content":{"rendered":"\n<ul class=\"wp-block-list\">\n<li><em>Neotorch<\/em><em>\u7814\u7a76\u662f\u5168\u7403\u9996\u4e2a\u6297PD-1\u5355\u6297\u7528\u4e8e\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u56f4\u624b\u672f\u671f\u6cbb\u7597\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u663e\u8457\u5ef6\u957f\u4e86\u65e0\u4e8b\u4ef6\u751f\u5b58\u671f\uff08EFS\uff09\uff0c\u75be\u75c5\u590d\u53d1\u3001\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u8fbe60%<\/em><em><\/em><\/li>\n\n\n\n<li><em>\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7ec4\u7684\u4e3b\u8981\u75c5\u7406\u7f13\u89e3\uff08MPR\uff09\u7387\u548c\u5b8c\u5168\u75c5\u7406\u7f13\u89e3\uff08pCR\uff09\u7387\u65b9\u9762\u5747\u4f18\u4e8e\u5355\u7eaf\u5316\u7597\u7ec4\uff0c\u5206\u522b\u4e3a48.5% vs 8.4%\u548c24.8% vs 1.0%<\/em><\/li>\n\n\n\n<li><em>\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7ec4\u7684\u603b\u751f\u5b58\u671f\uff08OS\uff09\u663e\u793a\u51fa\u660e\u663e\u7684\u83b7\u76ca\u8d8b\u52bf<\/em><\/li>\n<\/ul>\n\n\n\n<p>\u5317\u4eac\u65f6\u95f42023\u5e744\u670821\u65e5\uff0c\u541b\u5b9e\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u5ba3\u5e03\uff0c\u7531\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u6297PD-1\u5355\u6297\u836f\u7269\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7528\u4e8e\u53ef\u624b\u672f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u56f4\u624b\u672f\u671f\u6cbb\u7597III\u671f\u4e34\u5e8a\u7814\u7a76\uff08Neotorch\uff09\u6210\u679c\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u5728\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u5168\u4f53\u5927\u4f1a\u7cfb\u5217\uff08ASCO Plenary Series\uff094\u6708\u4f1a\u8bae\u4e0a\u8fdb\u884c\u4e86\u5168\u7403\u9996\u53d1\u516c\u5e03\u3002\u7814\u7a76\u8bc1\u5b9e\uff0c\u76f8\u8f83\u5355\u7eaf\u5316\u7597\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7528\u4e8e\u53ef\u624b\u672fIII\u671fNSCLC\u56f4\u624b\u672f\u671f\u6cbb\u7597\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005\u7684\u65e0\u4e8b\u4ef6\u751f\u5b58\u671f\uff08EFS\uff09\uff0c\u63d0\u5347\u4e3b\u8981\u75c5\u7406\u7f13\u89e3\uff08MPR\uff09\u7387\u548c\u5b8c\u5168\u75c5\u7406\u7f13\u89e3\uff08pCR\uff09\u7387\uff0c\u5e76\u4e14\u66f4\u591a\u60a3\u8005\u53ef\u901a\u8fc7\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u6cbb\u7597\u83b7\u5f97\u6839\u6cbb\u6027\u624b\u672f\u7684\u673a\u4f1a\u3002<\/p>\n\n\n\n<p>ASCO Plenary Series\u6bcf\u6708\u4e3e\u529e\u4e00\u6b21\uff0c\u901a\u8fc7ASCO\u4e13\u5bb6\u59d4\u5458\u4f1a\u6311\u9009\u81f3\u591a2\u7bc7\u975e\u5e38\u5177\u6709\u4ee3\u8868\u6027\u7684\u91cd\u78c5\u7814\u7a76\u6570\u636e\u8fdb\u884c\u516c\u5e03\u548c\u8ba8\u8bba\uff0c\u65e8\u5728\u53ca\u65f6\u66f4\u65b0\u5177\u6709\u521b\u65b0\u6027\u3001\u9ad8\u8d28\u91cf\u4ee5\u53ca\u91cd\u8981\u4e34\u5e8a\u5b9e\u8df5\u610f\u4e49\u7684\u4e34\u5e8a\u7814\u7a76\u6570\u636e\uff0c\u4fc3\u8fdb\u5168\u7403\u80bf\u7624\u6cbb\u7597\u65b9\u6848\u66f4\u65b0\uff0c\u60e0\u53ca\u60a3\u8005\u3002<\/p>\n\n\n\n<p>Neotorch\u7814\u7a76\uff08NCT04158440\uff09\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u6bd4\u8f83\u7279\u745e\u666e\u5229\u5355\u6297\u6216\u5b89\u6170\u5242\u8054\u5408\u5316\u7597\u7528\u4e8eII\/III\u671f\u53ef\u624b\u672fNSCLC\u60a3\u8005\u56f4\u624b\u672f\u671f\u6cbb\u7597\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\uff0c\u7531\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u9644\u5c5e\u80f8\u79d1\u533b\u9662\u9646\u821c\u6559\u6388\u7275\u5934\u5f00\u5c55\u30022023\u5e741\u6708\uff0cNeotorch\u7814\u7a76\u5b8c\u6210\u65b9\u6848\u9884\u8bbe\u7684\u671f\u4e2d\u5206\u6790\uff0c\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u6297PD-1\u5355\u6297\u7528\u4e8eNSCLC\u56f4\u624b\u672f\u671f\uff08\u6db5\u76d6\u65b0\u8f85\u52a9\u548c\u8f85\u52a9\u6cbb\u7597\uff09\u6cbb\u7597\u8fbe\u5230EFS\u9633\u6027\u7ed3\u679c\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n\n\n\n<p>Neotorch\u7814\u7a76\u5171\u7eb3\u5165404\u4f8bIII\u671fNSCLC\u60a3\u8005\uff0c\u4ee51:1\u7684\u6bd4\u4f8b\u88ab\u968f\u673a\u5206\u914d\u81f3\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7ec4\uff08n=202\uff09\u6216\u5b89\u6170\u5242\u8054\u5408\u5316\u7597\u7ec4\uff08n=202\uff09\uff0c\u5206\u522b\u63a5\u53d7\u7279\u745e\u666e\u5229\u5355\u6297\u6216\u5b89\u6170\u5242\u8054\u5408\u5316\u7597\u672f\u524d3\u5468\u671f\u53ca\u672f\u540e1\u5468\u671f\u6cbb\u7597\uff08\u9cde\u764c\u60a3\u8005\u5316\u7597\u65b9\u6848\u4e3a\u7d2b\u6749\u7c7b+\u94c2\u7c7b\uff0c\u975e\u9cde\u764c\u60a3\u8005\u5316\u7597\u65b9\u6848\u4e3a\u57f9\u7f8e\u66f2\u585e+\u94c2\u7c7b\uff09\uff0c\u968f\u540e\u63a5\u53d7\u7279\u745e\u666e\u5229\u5355\u6297\u6216\u5b89\u6170\u5242\u5de9\u56fa\u6cbb\u759713\u5468\u671f\u3002<\/p>\n\n\n\n<p>\u622a\u81f32022\u5e7411\u670830\u65e5\uff08\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f418.25\u4e2a\u6708\uff09\uff0c\u7ed3\u679c\u663e\u793a\uff1a\u4e0e\u5355\u7eaf\u5316\u7597\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7528\u4e8eIII\u671f\u53ef\u624b\u672fNSCLC\u60a3\u8005\u56f4\u624b\u672f\u671f\u6cbb\u7597\u5e76\u5728\u540e\u7eed\u8fdb\u884c\u7279\u745e\u666e\u5229\u5355\u6297\u5355\u836f\u5de9\u56fa\u6cbb\u7597\uff0c\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005EFS\uff08\u7814\u7a76\u8005\u8bc4\u4f30\u7684\u4e2d\u4f4dEFS\u5206\u522b\u4e3a\u5c1a\u672a\u6210\u719f vs 15.1\u4e2a\u6708\uff0cP<0.0001\uff09\uff0c\u75be\u75c5\u590d\u53d1\u3001\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u8fbe60%\uff08HR=0.40\uff0c95%CI\uff1a0.277-0.565\uff0c\u53cc\u4fa7P<0.0001\uff09\u3002\u4e24\u7ec4\u76841\u5e74EFS\u7387\u548c2\u5e74EFS\u7387\u5206\u522b\u4e3a84.4% vs 57.0%\u548c64.7% vs 38.7%\u3002<\/p>\n\n\n\n<p>\u540c\u65f6\uff0c\u7ecf\u76f2\u6001\u72ec\u7acb\u4e2d\u5fc3\u75c5\u7406\uff08BIPR\uff09\u8bc4\u4f30\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7ec4\u7684\u4e3b\u8981\u75c5\u7406\u7f13\u89e3\uff08MPR\uff09\u7387\u548c\u5b8c\u5168\u75c5\u7406\u7f13\u89e3\uff08pCR\uff09\u7387\u65b9\u9762\u5747\u4f18\u4e8e\u5355\u7eaf\u5316\u7597\u7ec4\uff0c\u5206\u522b\u4e3a48.5% vs 8.4%\uff08P\uff1c0.0001\uff09\u548c24.8% vs 1.0%\uff08P\uff1c0.0001\uff09\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7ec4\u7684\u603b\u751f\u5b58\u671f\uff08OS\uff09\u4e5f\u663e\u793a\u51fa\u660e\u663e\u7684\u83b7\u76ca\u8d8b\u52bf\u3002\u4e24\u7ec4\u4e2d\u4f4dOS\u5206\u522b\u4e3a\u672a\u6210\u719f vs 30.4\u4e2a\u6708\uff08HR=0.62\uff0c95% CI: 0.381-0.999\uff09\uff1b1\u5e74OS\u7387\u548c2\u5e74OS\u7387\u5206\u522b\u4e3a94.4% vs 89.6%\u548c81.2% vs 74.3%\u3002\u60a3\u8005\u5c06\u7ee7\u7eed\u8fdb\u884cOS\u968f\u8bbf\u3002<\/p>\n\n\n\n<p>\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u65b0\u8f85\u52a9\u6cbb\u7597\u540e\uff0c\u76f8\u6bd4\u5b89\u6170\u5242\u8054\u5408\u5316\u7597\u7ec4\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7ec4\u4e2d\u6709\u66f4\u9ad8\u6bd4\u4f8b\u7684\u60a3\u8005\u63a5\u53d7\u4e86\u6839\u6cbb\u76ee\u7684\u7684\u624b\u672f\uff0882.2% vs 73.3%\uff09\uff0c\u63d0\u793a\u5728\u5316\u7597\u57fa\u7840\u4e0a\u8054\u5408\u7279\u745e\u666e\u5229\u5355\u6297\u6cbb\u7597\u4e3a\u66f4\u591a\u60a3\u8005\u5e26\u6765\u4e86\u6839\u6cbb\u6027\u6cbb\u7597\u7684\u673a\u4f1a\u3002<\/p>\n\n\n\n<p>\u5b89\u5168\u6027\u65b9\u9762\uff0c\u4e24\u7ec4\u6cbb\u7597\u671f\u95f4\u51fa\u73b0\u7684\u4e0d\u826f\u4e8b\u4ef6\uff08TEAE\uff09\u53d1\u751f\u7387\u76f8\u4f3c\uff0c\u672a\u89c2\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002<\/p>\n\n\n\n<p>2023\u5e744\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u53d7\u7406\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u56f4\u624b\u672f\u671f\u6cbb\u7597\u5e76\u672c\u54c1\u5355\u836f\u4f5c\u4e3a\u8f85\u52a9\u6cbb\u7597\u540e\u5de9\u56fa\u6cbb\u7597\uff0c\u7528\u4e8e\u53ef\u5207\u9664III\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u6cbb\u7597\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n\n\n\n<p><strong>Neotorch<\/strong><strong>\u4e3b\u8981\u7814\u7a76\u8005\u3001\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u9644\u5c5e\u80f8\u79d1\u533b\u9662\u9646\u821c\u6559\u6388<\/strong>\u8868\u793a\uff1a\u201cNeotorch\u7814\u7a76\u5f00\u521b\u4e86\u5168\u7403\u9996\u4e2a\u20183+1+13\u2019NSCLC\u56f4\u624b\u672f\u671f\u6cbb\u7597\u6a21\u5f0f\uff0c\u5c06\u514d\u75ab\u6cbb\u7597\u8d2f\u7a7f\u672f\u524d\u65b0\u8f85\u52a9\u548c\u672f\u540e\u8f85\u52a9\u6cbb\u7597\u3002\u7ed3\u679c\u663e\u793a\uff0c\u5728\u5316\u7597\u57fa\u7840\u4e0a\u8054\u7528\u7279\u745e\u666e\u5229\u5355\u6297\u80fd\u591f\u663e\u8457\u5ef6\u957fNSCLC\u60a3\u8005\u7684EFS\uff0c2\u5e74EFS\u7387\u8fdc\u8d85\u5355\u7eaf\u5316\u7597\uff0c\u6570\u636e\u8868\u73b0\u4f18\u4e8e\u5df2\u62a5\u9053\u7684\u5176\u5b83\u7c7b\u4f3cIII\u671f\u7814\u7a76\uff0c\u4e0d\u4ec5\u5f70\u663e\u4e86\u4e2d\u56fd\u539f\u521b\u7814\u7a76\u7684\u5f3a\u5927\u5b9e\u529b\uff0c\u4e5f\u89c1\u8bc1\u4e86\u4e2d\u56fd\u539f\u521b\u7814\u7a76\u4ece\u8ddf\u8dd1\u5230\u9886\u8dd1\u7684\u5de8\u5927\u8f6c\u53d8\u3002\u4f5c\u4e3a\u8fc4\u4eca\u4e3a\u6b62\u4e2d\u56fd\u6700\u5927\u6837\u672c\u7684NSCLC\u56f4\u624b\u672f\u671f\u524d\u77bb\u6027III\u671f\u4e34\u5e8a\u7814\u7a76\uff0cNeotorch\u66f4\u8d34\u8fd1\u4e2d\u56fd\u4e34\u5e8a\u5b9e\u8df5\uff0c\u975e\u5e38\u671f\u5f85\u8fd9\u9879\u9996\u521b\u65b9\u6848\u80fd\u591f\u8fdb\u4e00\u6b65\u63d0\u5347\u6211\u56fd\u80ba\u764c\u514d\u75ab\u6cbb\u7597\u836f\u7269\u7684\u53ef\u53ca\u6027\uff0c\u4e3a\u60a3\u8005\u70b9\u71c3\u751f\u547d\u65b0\u5e0c\u671b\uff01\u201d<\/p>\n\n\n\n<p><strong>\u5927\u4f1a\u70b9\u8bc4\u4e13\u5bb6\u3001\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u4f69\u96f7\u5c14\u66fc\u533b\u5b66\u9662Charu Aggarwal\u6559\u6388<\/strong>\u8868\u793a\uff1a\u201cNeotorch\u7814\u7a76\u5efa\u7acb\u5728\u53ef\u624b\u672fNSCLC\u60a3\u8005\u5f53\u524d\u7684\u6807\u51c6\u7597\u6cd5\u2014\u2014\u672f\u524d\u514d\u75ab\u8054\u5408\u5316\u7597\u65b0\u8f85\u52a9\u6cbb\u7597\u4e4b\u4e0a\uff0c\u8bc1\u660e\u4e86\u4e00\u79cd\u56f4\u624b\u672f\u671f\u514d\u75ab\u6cbb\u7597\u6f5c\u5728\u65b0\u6a21\u5f0f\u3002\u201d<\/p>\n\n\n\n<p><strong>\u541b\u5b9e\u751f\u7269\u5168\u7403\u7814\u53d1\u603b\u88c1\u90b9\u5efa\u519b\u535a\u58eb<\/strong>\u8868\u793a\uff1a\u201c\u80ba\u764c\u662f\u5168\u7403\u6b7b\u4ea1\u7387\u6700\u9ad8\u7684\u6076\u6027\u80bf\u7624\uff0c\u5373\u4fbf\u65e9\u671f\u901a\u8fc7\u6839\u6cbb\u6027\u624b\u672f\u5207\u9664\u80bf\u7624\uff0c\u4ecd\u6709\u4e00\u5b9a\u6bd4\u4f8b\u7684\u60a3\u8005\u5728\u672f\u540e\u53d1\u751f\u590d\u53d1\u751a\u81f3\u6b7b\u4ea1\u3002\u5982\u4eca\uff0c\u514d\u75ab\u6cbb\u7597\u5df2\u5728\u591a\u79cd\u665a\u671f\u80bf\u7624\u6cbb\u7597\u4e2d\u786e\u7acb\u4e86\u6807\u51c6\u6cbb\u7597\u5730\u4f4d\uff0c\u800c\u9488\u5bf9\u75c5\u7a0b\u65e9\u671f\u7684\u5e94\u7528\u63a2\u7d22\u4e5f\u6e10\u5165\u4f73\u5883\u3002\u541b\u5b9e\u751f\u7269\u662f\u672c\u571f\u836f\u4f01\u4e2d\u5728\u80bf\u7624\u672f\u540e\u8f85\u52a9\/\u56f4\u624b\u672f\u671f\u6cbb\u7597\u9886\u57df\u6700\u5148\u5f00\u5c55\u4e34\u5e8a\u8bd5\u9a8c\u3001\u8986\u76d6\u9002\u5e94\u75c7\u6700\u5e7f\u7684\u4f01\u4e1a\u4e4b\u4e00\uff0c\u6b64\u6b21Neotorch\u7814\u7a76\u7684\u60ca\u8273\u6210\u679c\u66f4\u575a\u5b9a\u4e86\u6211\u4eec\u4e3a\u80bf\u7624\u60a3\u8005\u5bfb\u6c42\u6cbb\u6108\u5e0c\u671b\u7684\u51b3\u5fc3\u3002\u76ee\u524d\u57fa\u4e8eNeotorch\u6570\u636e\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u6b63\u5728\u63a5\u53d7\u4e2d\u56fd\u836f\u76d1\u673a\u6784\u5ba1\u8bc4\uff0c\u671f\u5f85\u5728\u5404\u65b9\u7684\u5171\u540c\u52aa\u529b\u4e0b\u63a8\u52a8\u8fd9\u9879\u521b\u65b0\u7597\u6cd5\u53ca\u65e9\u60e0\u53ca\u672c\u571f\u80ba\u764c\u60a3\u8005\uff01\u201d<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u3010\u53c2\u8003\u6587\u732e\u3011<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">1.ASCO\u5b98\u7f51<\/h5>\n\n\n\n<p><\/p>\n\n\n\n<h6 class=\"wp-block-heading\"><em>1.&nbsp;<\/em><em>\u672c\u6750\u6599\u65e8\u5728\u4f20\u9012\u524d\u6cbf\u4fe1\u606f\uff0c\u65e0\u610f\u5411\u60a8\u505a\u4efb\u4f55\u4ea7\u54c1\u7684\u63a8\u5e7f\uff0c\u4e0d\u4f5c\u4e3a\u4e34\u5e8a\u7528\u836f\u6307\u5bfc\u3002<\/em><\/h6>\n\n\n\n<h6 class=\"wp-block-heading\"><em>2. \u82e5\u60a8\u60f3\u4e86\u89e3\u5177\u4f53\u75be\u75c5\u8bca\u7597\u4fe1\u606f\uff0c\u8bf7\u9075\u4ece\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u7684\u610f\u89c1\u4e0e\u6307\u5bfc\u3002<\/em><\/h6>\n\n\n\n\n\n<p><strong>\u5173\u4e8e\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09<\/strong><\/p>\n\n\n\n<p>\u80ba\u764c\u662f\u76ee\u524d\u5168\u7403\u53d1\u75c5\u7387\u7b2c\u4e8c\u3001\u6b7b\u4ea1\u7387\u7b2c\u4e00\u7684\u6076\u6027\u80bf\u7624<sup>1<\/sup>\u3002\u636e\u7edf\u8ba1\uff0c2020\u5e74\u4e2d\u56fd\u7684\u80ba\u764c\u75c5\u4f8b\u6570\u5360\u65b0\u53d1\u764c\u75c7\u75c5\u4f8b\u6570\u768417.9%\uff0881.6\u4e07\uff09\uff0c\u764c\u75c7\u6b7b\u4ea1\u75c5\u4f8b\u6570\u768423.8%\uff0871.5\u4e07\uff09<sup>2<\/sup>\u3002NSCLC\u4e3a\u80ba\u764c\u7684\u4e3b\u8981\u4e9a\u578b\uff0c\u7ea6\u5360\u6240\u6709\u75c5\u4f8b\u768485%<sup>3<\/sup>\u3002\u5176\u4e2d\uff0c20-25%\u7684\u60a3\u8005\u521d\u8bca\u53ef\u624b\u672f\u5207\u9664<sup>4<\/sup>\uff0c\u4f46\u5373\u4fbf\u63a5\u53d7\u4e86\u6839\u6cbb\u6027\u624b\u672f\u6cbb\u7597\uff0c\u4ecd\u670930-55%\u7684\u60a3\u8005\u4f1a\u5728\u672f\u540e\u53d1\u751f\u590d\u53d1\u5e76\u6b7b\u4ea1<sup>5,6<\/sup>\u3002\u6839\u6cbb\u6027\u624b\u672f\u8054\u5408\u5316\u7597\u662f\u9884\u9632\u75be\u75c5\u590d\u53d1\u7684\u624b\u6bb5\u4e4b\u4e00\uff0c\u4f46\u5316\u7597\u4f5c\u4e3a\u672f\u524d\u65b0\u8f85\u52a9\u6216\u672f\u540e\u8f85\u52a9\u6cbb\u7597\u7684\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\uff0c\u4ec5\u80fd\u5c06\u60a3\u8005\u76845\u5e74\u751f\u5b58\u7387\u63d0\u9ad8\u7ea65%<sup>7,8<\/sup>\u3002<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">\u3010\u53c2\u8003\u6587\u732e\u3011<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">1. https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/15-Lung-fact-sheet.pdf.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">2. https:\/\/gco.iarc.fr\/today\/data\/factsheets\/populations\/160-china-fact-sheets.pdf.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">3. Molina JR, et al. Mayo Clin. Proc. 2008; 83(5), 584\u2013594.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">4. Liang Y, et al.&nbsp; Transl Lung Cancer Res 2013;2:403-10.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">5. Uramoto H, et al. Transl Lung Cancer Res 2014;3:242-9.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">6. Taylor MD, et al. Ann Thorac Surg 2012;93:1813-20.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">7. Pignon JP, et al. J Clin Oncol 2008; 26:3552-3559.<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">8. NSCLC Meta-analysis Collaborative Group. Lancet&nbsp; 2014 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Plenary 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