{"id":2501,"date":"2023-10-20T10:02:22","date_gmt":"2023-10-20T10:02:22","guid":{"rendered":"https:\/\/www.junshipharma.com\/?p=2501"},"modified":"2024-01-03T16:52:18","modified_gmt":"2024-01-03T08:52:18","slug":"%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e5%9c%a82023-esmo%e5%b9%b4%e4%bc%9a%e5%b1%95%e7%a4%ba%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%9711%e9%a1%b9%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e6%88%90","status":"publish","type":"post","link":"https:\/\/www.junshipharma.com\/%e5%90%9b%e5%ae%9e%e7%94%9f%e7%89%a9%e5%9c%a82023-esmo%e5%b9%b4%e4%bc%9a%e5%b1%95%e7%a4%ba%e7%89%b9%e7%91%9e%e6%99%ae%e5%88%a9%e5%8d%95%e6%8a%9711%e9%a1%b9%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e6%88%90\/","title":{"rendered":"\u541b\u5b9e\u751f\u7269\u57282023 ESMO\u5e74\u4f1a\u5c55\u793a\u7279\u745e\u666e\u5229\u5355\u629711\u9879\u6700\u65b0\u7814\u7a76\u6210\u679c"},"content":{"rendered":"\n

10\u670820\u65e5\u81f324\u65e5\uff0c2023\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5927\u4f1a\u5728\u897f\u73ed\u7259\u9a6c\u5fb7\u91cc\u76db\u5927\u53ec\u5f00\u3002\u541b\u5b9e\u751f\u7269\u80bf\u7624\u514d\u75ab\uff08I-O\uff09\u521b\u65b0\u4ea7\u54c1\u7279\u745e\u666e\u5229\u5355\u6297\uff08\u6297PD-1\u5355\u6297\uff09\u517111\u9879\u7814\u7a76\u6210\u679c\u5165\u9009\u672c\u6b21\u5927\u4f1a\uff0c\u5305\u62ec1\u9879\u6700\u65b0\u7a81\u7834\u6458\u8981\uff08Late-breaking Abstracts\uff0cLBA\uff09\u30012\u9879\u4f18\u9009\u53e3\u5934\u62a5\u544a\uff08Proffered Paper Session\uff09\u30018\u9879\u5899\u62a5\uff0c\u8986\u76d6\u80ba\u764c\u3001\u80be\u764c\u3001\u5934\u9888\u764c\u3001\u4e73\u817a\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u3001\u5bab\u9888\u764c\u3001\u80f8\u817a\u764c\u3001\u6dcb\u5df4\u7624\u7b49\u5341\u4e2a\u9886\u57df\uff0c\u83b7\u5f97\u5168\u7403\u5173\u6ce8\u3002<\/p>\n\n\n\n

\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5927\u4f1a\u662f\u6b27\u6d32\u6700\u8d1f\u76db\u540d\u548c\u6700\u5177\u5f71\u54cd\u529b\u7684\u80bf\u7624\u5b66\u4f1a\u8bae\uff0c\u6bcf\u5e74\u90fd\u6709\u8d85\u8fc730,000\u540d\u4e13\u4e1a\u4eba\u58eb\u53c2\u52a0\u4f1a\u8bae\uff0c\u5c31\u80bf\u7624\u5185\u79d1\u9886\u57df\u70ed\u95e8\u8bdd\u9898\u8fdb\u884c\u63a2\u8ba8\uff0c\u4f20\u64ad\u6700\u65b0\u524d\u6cbf\u6570\u636e\uff0c\u4e3a\u4e16\u754c\u5404\u5730\u80bf\u7624\u5b66\u5bb6\u53ca\u76f8\u5173\u4eba\u5458\u63d0\u4f9b\u4ea4\u6d41\u673a\u4f1a\u3002ESMO\u5e74\u5ea6\u5927\u4f1a\u5df2\u6210\u4e3a\u80bf\u7624\u9886\u57df\u8f6c\u5316\u7814\u7a76\u3001\u591a\u5b66\u79d1\u8ba8\u8bba\u7684\u5353\u8d8a\u5168\u7403\u5e73\u53f0\u3002<\/p>\n\n\n\n

\u541b\u5b9e\u751f\u7269\u5168\u7403\u7814\u53d1\u603b\u88c1\u90b9\u5efa\u519b\u535a\u58eb<\/strong>\u8868\u793a\uff1a”\u6b64\u6b21ESMO\u5927\u4f1a\u5c55\u793a\u4e86\u6211\u4eec\u6700\u65b0\u768412\u9879\u7814\u7a76\u6210\u679c\u3002\u5176\u4e2d\uff0c\u5c0f\u7ec6\u80de\u80ba\u764c\u7814\u7a76EXTENTORCH\u4ee5\u53ca\u80be\u764c\u7814\u7a76RENOTORCH\u5747\u4e3a\u9996\u6b21\u4eae\u76f8\u3002\u968f\u7740\u2018PD-1+X\u2019\u8054\u5408\u7597\u6cd5\u5728\u66f4\u591a\u9002\u5e94\u75c7\u9886\u57df\u53d6\u5f97\u4e34\u5e8a\u8fdb\u5c55\uff0c\u5c06\u8fdb\u4e00\u6b65\u592f\u5b9e\u541b\u5b9e\u751f\u7269\u591a\u5e74\u6765\u81f4\u529b\u6253\u9020\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7ba1\u7ebf\u5b9e\u529b\u3002\u201d<\/p>\n\n\n\n\n\n

RENOTORCH\u7814\u7a76\uff1a\u4e2d\u4f4dPFS\u8fbe18.0\u4e2a\u6708\uff01\u5237\u65b0\u665a\u671f\u80be\u764c\u4e00\u7ebf\u514d\u75ab\u9776\u5411\u6cbb\u7597\u83b7\u76ca\u8bb0\u5f55<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n
\u6765\u6e90\uff1aAnnals of Oncology\u5b98\u7f51<\/em><\/h6>\n\n\n\n

<\/p>\n\n\n\n

\u7531\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u90ed\u519b\u6559\u6388\u548c\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u4ec1\u6d4e\u533b\u9662\u9ec4\u7ffc\u7136\u6559\u6388\u8054\u5408\u7275\u5934\u5f00\u5c55\u7684\u56fd\u5185\u9996\u4e2a\u665a\u671f\u80be\u764c\u514d\u75ab\u6cbb\u7597\u5173\u952e\u2162\u671f\u4e34\u5e8a\u7814\u7a76RENOTORCH\u7814\u7a76\u6210\u679c\u5728ESMO\u5927\u4f1a\u4f18\u9009\u53e3\u5934\u62a5\u544a\u4e13\u573a\u4f1a\u8bae\u4e0a\u9996\u6b21\u53d1\u5e03\uff0c\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u76db\u9521\u6960\u6559\u6388\u62a5\u544a\u4e86\u7814\u7a76\u8be6\u7ec6\u7ed3\u679c\u3002\u5168\u6587\u540c\u6b65\u83b7ESMO\u5b98\u65b9\u671f\u520a\u300a\u80bf\u7624\u5b66\u5e74\u9274\u300b\uff08Annals of Oncology<\/em>\uff1b\u5f71\u54cd\u56e0\u5b50\uff1a50.5\uff1b\u80bf\u7624\u9886\u57df\u5168\u7403\u6392\u540dTOP5\u7684\u9876\u7ea7\u671f\u520a\uff09\u53d1\u8868\uff0c\u5438\u5f15\u4e86\u56fd\u9645\u5b66\u8005\u7684\u5e7f\u6cdb\u5173\u6ce8\u3002<\/p>\n\n\n\n

RENOTORCH\u7814\u7a76\uff08NCT04394975\uff09\u662f\u4e00\u9879\u968f\u673a\u3001\u5f00\u653e\u6807\u7b7e\u3001\u591a\u4e2d\u5fc3\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u5171\u7eb3\u5165421\u4f8b\u65e2\u5f80\u672a\u63a5\u53d7\u4efb\u4f55\u7cfb\u7edf\u6cbb\u7597\u7684\u4e2d\u9ad8\u5371\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u80be\u7ec6\u80de\u764c\uff08RCC\uff09\u60a3\u8005\uff0c\u5728\u5168\u56fd47\u5bb6\u4e34\u5e8a\u4e2d\u5fc3\u5f00\u5c55\uff0c\u4e3a\u6211\u56fd\u9996\u4e2a\u665a\u671f\u80be\u764c\u514d\u75ab\u6cbb\u7597\u5173\u952eIII\u671f\u7814\u7a76\u3002<\/p>\n\n\n\n

\u622a\u81f32023\u5e743\u670831\u65e5\uff08\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f4\u4e3a14.6\u4e2a\u6708\uff09\uff0cRENOTORCH\u671f\u4e2d\u5206\u6790\u7ed3\u679c\u663e\u793a\uff0c\u4e0e\u8212\u5c3c\u66ff\u5c3c\u5355\u836f\u6cbb\u7597\u76f8\u6bd4\uff0c\u63a5\u53d7\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u963f\u6614\u66ff\u5c3c\u4e00\u7ebf\u6cbb\u7597\u53ef\u663e\u8457\u6539\u5584\u60a3\u8005\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u3001\u63d0\u5347\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\uff0c\u4e14\u5b89\u5168\u6027\u826f\u597d\u3002<\/p>\n\n\n\n

    \n
  • \u4e0e\u8212\u5c3c\u66ff\u5c3c\u5355\u836f\u6cbb\u7597\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u963f\u6614\u66ff\u5c3c\u6cbb\u7597\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005PFS\uff0c\u76f2\u6001\u72ec\u7acb\u4e2d\u5fc3\u9605\u7247\uff08BICR\uff09\u8bc4\u4f30\u7684\u4e2d\u4f4dPFS\u4e3a18.0 vs. 9.8\u4e2a\u6708\uff0c\u60a3\u8005PFS\u5ef6\u957f\u8fd12\u500d\uff0c\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e35%\uff08HR=0.65\uff1b95%CI\uff1a0.49-0.86\uff1bP=0.0028\uff09\u3002\u4e24\u7ec41\u5e74\u548c2\u5e74PFS\u7387\u5206\u522b\u4e3a62.7% vs. 45.4%\u548c44.6% vs. 30.2%\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u4e0d\u540c\u4e8e\u65e2\u5f80\u540c\u7c7b\u578b\u7814\u7a76\u7eb3\u5165\u5168\u90e8\u98ce\u9669\u6c34\u5e73\u7684\u60a3\u8005\uff0c\u672c\u7814\u7a76\u4ec5\u7eb3\u5165\u4e2d\u9ad8\u5371\u60a3\u8005\uff0c\u4ecd\u53d6\u5f97\u4e86\u76ee\u524d\u5df2\u62a5\u544a\u7684\u540c\u7c7b\u578b\u7814\u7a76\u4e2d\u7684\u6700\u957f\u4e2d\u4f4dPFS\u3002<\/li>\n\n\n\n
  • \u4e0e\u8212\u5c3c\u66ff\u5c3c\u5355\u836f\u6cbb\u7597\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u963f\u6614\u66ff\u5c3c\u7ec4\u60a3\u8005\u7684ORR\u66f4\u4f18\uff08BICR\u8bc4\u4f30\u7684ORR\u4e3a56.7% vs. 30.8%\uff0cP<0.0001\uff09\uff0c\u5e76\u4e14\u80bf\u7624\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DoR\uff09\u66f4\u957f\uff08\u4e2d\u4f4dDoR\u4e3a\u5c1a\u672a\u8fbe\u5230 vs. 16.7\u4e2a\u6708\uff1bHR=0.614\uff1b95%CI\uff1a0.340-1.137\uff09\u3002<\/li>\n\n\n\n
  • \u4e0e\u8212\u5c3c\u66ff\u5c3c\u5355\u836f\u7ec4\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u963f\u6614\u66ff\u5c3c\u7ec4\u5177\u6709\u660e\u663e\u7684\u603b\u751f\u5b58\u671f\uff08OS\uff09\u83b7\u76ca\u8d8b\u52bf\uff08\u4e2d\u4f4dOS\u4e3a\u5c1a\u672a\u8fbe\u5230 vs. 26.8\u4e2a\u6708\uff09\uff0c\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e39%\uff08HR=0.61\uff1b95%CI\uff1a0.40-0.92\uff09\u30021\u5e74\u548c2\u5e74OS\u7387\u5206\u522b\u4e3a90.5% vs. 81.9%\u548c71.8% vs. 63.2%\u3002<\/li>\n\n\n\n
  • \u5b89\u5168\u6027\u65b9\u9762\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u963f\u6614\u66ff\u5c3c\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u53d1\u73b0\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002<\/li>\n<\/ul>\n\n\n\n

    \u57fa\u4e8eRENOTORCH\u7814\u7a76\u79ef\u6781\u7ed3\u679c\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u4e8e\u4eca\u5e747\u6708\u6b63\u5f0f\u53d7\u7406\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u963f\u6614\u66ff\u5c3c\u7528\u4e8e\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027RCC\u60a3\u8005\u4e00\u7ebf\u6cbb\u7597\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n\n\n\n

    <\/p>\n\n\n\n

    EXTENTORCH\u7814\u7a76\uff1a\u5168\u7403\u9996\u4e2aSCLC PD-1\u514d\u75ab\u6cbb\u7597\u2162\u671f\u7814\u7a76\u8fbe\u5230\u201c\u53cc\u9633\u201d\u7ed3\u679c<\/strong><\/p>\n\n\n\n

    \u7531\u5409\u6797\u7701\u80bf\u7624\u533b\u9662\u7a0b\u9896\u6559\u6388\u7275\u5934\u5f00\u5c55\u7684\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u5e7f\u6cdb\u671f\u5c0f\u7ec6\u80de\u80ba\u764c\uff08ES-SCLC\uff09\u7684\u2162\u671f\u7814\u7a76EXTENTORCH\u4ee5\u5927\u4f1a\u6700\u65b0\u7a81\u7834\u6458\u8981\uff08LBA\uff09\u5f62\u5f0f\u9996\u6b21\u4eae\u76f8\u8ff7\u4f60\u53e3\u5934\u62a5\u544a\u4e13\u573a\uff0c\u5409\u6797\u7701\u80bf\u7624\u533b\u9662\u67f3\u5f71\u6559\u6388\u5728\u4f1a\u4e0a\u62a5\u544a\u4e86\u7814\u7a76\u8be6\u7ec6\u7ed3\u679c\u3002<\/p>\n\n\n\n

    EXTENTORCH\u7814\u7a76\uff08NCT04012606\uff09\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u6bd4\u8f83\u7279\u745e\u666e\u5229\u5355\u6297\u6216\u5b89\u6170\u5242\u8054\u5408\u4f9d\u6258\u6cca\u82f7\u53ca\u94c2\u7c7b\u4e00\u7ebf\u6cbb\u7597ES-SCLC\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u5171\u7eb3\u5165442\u4f8b\u65e2\u5f80\u672a\u63a5\u53d7\u7cfb\u7edf\u6cbb\u7597\u7684ES-SCLC\u60a3\u8005\uff0c\u5728\u5168\u56fd51\u5bb6\u4e34\u5e8a\u7814\u7a76\u4e2d\u5fc3\u8054\u5408\u5f00\u5c55\u3002\u4eca\u5e745\u6708\uff0cEXTENTORCH\u7814\u7a76\u6210\u529f\u8fbe\u5230\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u7531\u6b64\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u5728ES-SCLC\u4e00\u7ebf\u6cbb\u7597\u2162\u671f\u7814\u7a76\u4e2d\u8fbe\u6210OS\u548cPFS\u53cc\u91cd\u4e3b\u8981\u7ec8\u70b9\u7684PD-1\u6291\u5236\u5242\u3002<\/p>\n\n\n\n

    ENTENTORCH\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u76f8\u8f83\u5355\u7eaf\u5316\u7597\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u5e76\u4f7f\u7528\u7279\u745e\u666e\u5229\u5355\u6297\u7ef4\u6301\u6cbb\u7597\u7684ES-SCLC\u60a3\u8005\uff0cPFS\u548cOS\u5747\u663e\u8457\u5ef6\u957f\u3001\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u6709\u671b\u6210\u4e3aES-SCLC\u7684\u4e00\u7ebf\u6807\u51c6\u7597\u6cd5\u3002<\/p>\n\n\n\n

      \n
    • \u6700\u7ec8PFS\u5206\u6790\uff08\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f4\u4e3a11.8\u4e2a\u6708\uff09\u663e\u793a\uff0c\u4e0e\u5355\u7eaf\u5316\u7597\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u663e\u8457\u6539\u5584\u60a3\u8005PFS\uff08\u7814\u7a76\u8005\u8bc4\u4f30\u7684\u4e2d\u4f4dPFS\u4e3a5.8 vs. 5.6\u4e2a\u6708\uff09\uff0c\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e33.3%\uff08HR=0.667\uff1b95% CI\uff1a0.539-0.824\uff1bP=0.0002\uff09\u3002<\/li>\n\n\n\n
    • \u6700\u7ec8OS\u5206\u6790\uff08\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f4\u4e3a13.7\u4e2a\u6708\uff09\u663e\u793a\uff0c\u4e0e\u5355\u7eaf\u5316\u7597\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u751f\u5b58\u83b7\u76ca\u663e\u8457\uff08\u4e2d\u4f4dOS\u4e3a14.6 vs. 13.3\u4e2a\u6708\uff09\uff0c\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u4e8620.2%\uff08HR=0.798\uff1b95% CI\uff1a0.648-0.982\uff1bP=0.0327\uff09\u3002<\/li>\n\n\n\n
    • \u751f\u7269\u6807\u5fd7\u7269\u63a2\u7d22\u5206\u6790\u53d1\u73b0\uff0c\u65e0\u8bba\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08TMB\uff09\u72b6\u6001\u5982\u4f55\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7ec4\u7684PFS\u548cOS\u5747\u6709\u6539\u5584\u3002\u6b64\u5916\uff0c\u9ecf\u7740\u6591\/\u6574\u5408\u7d20\u4fe1\u53f7\u901a\u8def\u7a81\u53d8\u4e0e\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u60a3\u8005PFS\u548cOS\u4e0d\u826f\u9884\u540e\u76f8\u5173\u3002<\/li>\n\n\n\n
    • \u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7684\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u53d1\u73b0\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002<\/li>\n<\/ul>\n\n\n\n

      \u57fa\u4e8eEXTENTORCH\u7684\u79ef\u6781\u7ed3\u679c\uff0cNMPA\u5df2\u4e8e\u4eca\u5e747\u6708\u6b63\u5f0f\u53d7\u7406\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u4f9d\u6258\u6cca\u82f7\u548c\u94c2\u7c7b\u7528\u4e8eES-SCLC\u4e00\u7ebf\u6cbb\u7597\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n\n\n\n

      <\/p>\n\n\n\n

      \u7279\u745e\u666e\u5229\u5355\u6297\u6dcb\u5df4\u7624\u7814\u7a76\uff1aCR\u7387\u8fbe77.3%\uff0c\u4e3a\u5316\u7597\u4e0d\u4f73\u7684I\/Il\u671fENKTL\u60a3\u8005\u5e26\u6765\u66f4\u591a\u6cbb\u6108\u53ef\u80fd<\/strong><\/p>\n\n\n\n

      \u7531\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\u848b\u660e\u6559\u6388\u7275\u5934\u5f00\u5c55\u7684\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u653e\u7597\u7528\u4e8e\u2160\/\u2161\u671f\u7ed3\u5916NK\/T\u7ec6\u80de\u6dcb\u5df4\u7624\uff08ENKTL\uff09\u7684\u2161\u671f\u4e34\u5e8a\u7814\u7a76\uff08ChiCTR2100045147\uff09\u5728ESMO\u5927\u4f1a\u4f18\u9009\u53e3\u5934\u62a5\u544a\u8840\u6db2\u6076\u6027\u80bf\u7624\u4e13\u573a\u516c\u5e03\u4e86\u8be6\u7ec6\u7ed3\u679c\u3002<\/p>\n\n\n\n

      ENKTL\u662f\u4e00\u79cd\u9884\u540e\u8f83\u5dee\u7684\u4fb5\u88ad\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff0c\u5e38\u89c1\u4e8e\u4e9a\u6d32\u4eba\u7fa4\uff0c\u521d\u8bca\u65f6\u5927\u591a\u4e3a\u2160\/\u2161\u671f\u3002\u76ee\u524d\u4e34\u5e8a\u4e0a\u5e38\u91c7\u7528\u4ee5L-\u5929\u51ac\u9170\u80fa\u6216\u57f9\u95e8\u51ac\u9176\u4e3a\u57fa\u7840\u7684\u591a\u836f\u5316\u7597\u8054\u5408\u653e\u7597\uff08CCRT\uff09\u7684\u6807\u51c6\u6cbb\u7597\u65b9\u6848\u6cbb\u7597\u65b0\u8bca\u65ad\u7684\u5c40\u9650\u6027ENKTL\uff0c\u4f46\u65e0\u8bba\u91c7\u7528\u4f55\u79cd\u653e\u5316\u7597\u8054\u5408\u65b9\u5f0f\uff0c\u60a3\u80055\u5e74\u751f\u5b58\u7387\u901a\u5e38\u572860%-70%\uff0c\u5e76\u4e14\u5bf9\u4e8e\u591a\u836f\u5316\u7597\u53cd\u5e94\u4e0d\u4f73\u7684ENKTL\u60a3\u8005\uff0c\u5176\u751f\u5b58\u671f\u660e\u663e\u8f83\u4f4e\uff0c\u4e34\u5e8a\u9700\u6c42\u4e9f\u5f85\u6ee1\u8db3\u3002<\/p>\n\n\n\n

      \u8be5\u7814\u7a76\u4e3a\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u3001\u5355\u81c2\u7684\u2161\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u7eb3\u5165\u4e8622\u4f8b\u65e2\u5f80\u63a5\u53d7\u653e\u75972-3\u4e2a\u5468\u671f\u540e\u672a\u8fbe\u5b8c\u5168\u7f13\u89e3\uff08CR\uff09\u7684\u2160\/\u2161\u671fENKTL\u60a3\u8005\u3002\u7ed3\u679c\u8868\u660e\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u653e\u7597\u53ef\u6709\u6548\u6cbb\u7597\u5bf9\u5316\u7597\u53cd\u5e94\u4e0d\u4f73\u7684I\/II\u671fENKTL\u60a3\u8005\uff0c\u63d0\u9ad8\u4e34\u5e8a\u7597\u6548\u7684\u540c\u65f6\u53c8\u53ef\u4ee5\u907f\u514d\u4e0d\u5fc5\u8981\u7684\u7528\u836f\uff0c\u5e76\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u89c2\u5bdf\u5230\u5176\u4ed6\u6bd2\u6027\uff0c\u503c\u5f97\u8fdb\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n\n\n\n

        \n
      • \u6574\u4f53ORR\u4e3a90.9%\uff0cCR\u7387\u8fbe77.3%\uff0817\u4f8b\uff09\uff0c3\u4f8b\u8fbe\u5230PR\uff0813.6%\uff09\u3002<\/li>\n\n\n\n
      • \u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f4\u4e3a23\u4e2a\u6708\uff0c\u4e2d\u4f4dPFS\u548c\u4e2d\u4f4dOS\u5747\u5c1a\u672a\u8fbe\u5230\uff0c2\u5e74PFS\u7387\u548cOS\u7387\u5206\u522b\u4e3a81.6%\u548c95.0%\u3002<\/li>\n\n\n\n
      • \u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u53d1\u751f3\u7ea7\u4ee5\u4e0a\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff08TRAE\uff09\u3002<\/li>\n\n\n\n
      • \u7814\u7a76\u8005\u8fd8\u8ba4\u4e3a\uff0c\u65e9\u671f\u4f7f\u752818F-FDG PET\/CT\u53ef\u4ee5\u8bc6\u522b\u5bf9\u4ee5\u5929\u51ac\u9170\u80fa\u9176\u4e3a\u57fa\u7840\u7684\u5316\u7597\u65e0\u5e94\u7b54\u7684ENKTL\u60a3\u8005\u3002<\/li>\n<\/ul>\n\n\n","protected":false},"excerpt":{"rendered":"

        10\u670820\u65e5\u81f324\u65e5\uff0c2023\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5927\u4f1a\u5728\u897f\u73ed\u7259\u9a6c\u5fb7\u91cc\u76db\u5927\u53ec\u5f00\u3002\u541b\u5b9e\u751f\u7269\u80bf\u7624\u514d\u75ab\uff08I-O\uff09\u521b\u65b0\u4ea7\u54c1\u7279\u745e\u666e\u5229\u5355\u6297\uff08\u6297PD-1\u5355\u6297\uff09\u517111\u9879\u7814\u7a76\u6210\u679c\u5165\u9009\u672c\u6b21\u5927\u4f1a\uff0c\u5305\u62ec1\u9879\u6700\u65b0\u7a81\u7834\u6458\u8981\uff08Late-breaking Abstracts\uff0cLBA\uff09\u30012\u9879\u4f18\u9009\u53e3\u5934\u62a5\u544a\uff08Proffered Paper Session\uff09\u30018\u9879\u5899\u62a5\uff0c\u8986\u76d6\u80ba\u764c\u3001\u80be\u764c\u3001\u5934\u9888\u764c\u3001\u4e73\u817a\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u3001\u5bab\u9888\u764c\u3001\u80f8\u817a\u764c\u3001\u6dcb\u5df4\u7624\u7b49\u5341\u4e2a\u9886\u57df\uff0c\u83b7\u5f97\u5168\u7403\u5173\u6ce8\u3002<\/p>\n","protected":false},"author":3,"featured_media":2515,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2501","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1"],"yoast_head":"\n\u541b\u5b9e\u751f\u7269\u57282023 ESMO\u5e74\u4f1a\u5c55\u793a\u7279\u745e\u666e\u5229\u5355\u629711\u9879\u6700\u65b0\u7814\u7a76\u6210\u679c - \u541b\u5b9e\u751f\u7269<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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content=\"10\u670820\u65e5\u81f324\u65e5\uff0c2023\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5927\u4f1a\u5728\u897f\u73ed\u7259\u9a6c\u5fb7\u91cc\u76db\u5927\u53ec\u5f00\u3002\u541b\u5b9e\u751f\u7269\u80bf\u7624\u514d\u75ab\uff08I-O\uff09\u521b\u65b0\u4ea7\u54c1\u7279\u745e\u666e\u5229\u5355\u6297\uff08\u6297PD-1\u5355\u6297\uff09\u517111\u9879\u7814\u7a76\u6210\u679c\u5165\u9009\u672c\u6b21\u5927\u4f1a\uff0c\u5305\u62ec1\u9879\u6700\u65b0\u7a81\u7834\u6458\u8981\uff08Late-breaking Abstracts\uff0cLBA\uff09\u30012\u9879\u4f18\u9009\u53e3\u5934\u62a5\u544a\uff08Proffered Paper Session\uff09\u30018\u9879\u5899\u62a5\uff0c\u8986\u76d6\u80ba\u764c\u3001\u80be\u764c\u3001\u5934\u9888\u764c\u3001\u4e73\u817a\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u3001\u5bab\u9888\u764c\u3001\u80f8\u817a\u764c\u3001\u6dcb\u5df4\u7624\u7b49\u5341\u4e2a\u9886\u57df\uff0c\u83b7\u5f97\u5168\u7403\u5173\u6ce8\u3002\" \/>\n<meta property=\"og:url\" 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