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JUPITER-02\u7814\u7a76\u662f\u9f3b\u54bd\u764c\u514d\u75ab\u6cbb\u7642\u9818\u57df\u9996\u500b\u570b\u969b\u591a\u4e2d\u5fc3\u3001\u6a23\u672c\u91cf\u6700\u5927\u7684\u96d9\u76f2\u3001\u96a8\u6a5f\u5c0d\u7167\u2162\u671f\u81e8\u5e8a\u7814\u7a76\u3002\u5176\u7814\u7a76\u6210\u679c\u5148\u5f8c\u57282021\u5e74\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703\uff08ASCO\uff09\u5e74\u6703\u5168\u9ad4\u5927\u6703\uff08#LBA2\uff09\u3001\u300a\u81ea\u7136-\u91ab\u5b78\u300b\uff08Nature Medicine<\/em>\uff0c\u5f71\u97ff\u56e0\u6578\uff1a82.9\uff09\u3001\u300a\u7f8e\u570b\u91ab\u5b78\u6703\u96dc\u8a8c\u300b\uff08JAMA<\/em>\uff0c\u5f71\u97ff\u56e0\u6578\uff1a120.7\uff09\u767c\u8868\u3002\u7814\u7a76\u7d50\u679c\u8868\u660e\uff0c\u8207\u55ae\u7d14\u5316\u7642\u76f8\u6bd4\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u4e00\u7dda\u6cbb\u7642\u5fa9\u767c\/\u8f49\u79fb\u6027\u9f3b\u54bd\u764c\u53ef\u986f\u8457\u5ef6\u9577\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\uff0c\u4e2d\u4f4dPFS\u9054\u523021.4\u500b\u6708\uff0c3\u5e74OS\u7387\u9054\u523064.5%\uff0c\u4f7f\u60a3\u8005\u7684\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e48%\uff0c\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e37%\uff0c\u4e14\u5b89\u5168\u6027\u826f\u597d\u53ef\u63a7\u3002<\/p>\n\n\n\n

POLARIS-02\u7814\u7a76\u7d50\u679c\u5df2\u65bc2021\u5e741\u6708\u7dda\u4e0a\u767c\u8868\u65bc\u300a\u81e8\u5e8a\u816b\u7624\u5b78\u96dc\u8a8c\u300b\uff08Journal of Clinical Oncology<\/em>\uff0c\u5f71\u97ff\u56e0\u6578\uff1a45.3\uff09\u3002\u7814\u7a76\u7d50\u679c\u986f\u793a\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u5728\u65e2\u5f80\u5316\u7642\u5931\u6557\u7684\u5fa9\u767c\/\u8f49\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u4e2d\u8868\u73fe\u51fa\u6301\u4e45\u7684\u6297\u816b\u7624\u6d3b\u6027\u548c\u53ef\u63a7\u7684\u5b89\u5168\u6027\uff0c\u60a3\u8005\u5ba2\u89c0\u7de9\u89e3\u7387\uff08ORR\uff09\u70ba20.5%\uff0c\u4e2d\u4f4d\u7de9\u89e3\u6301\u7e8c\u6642\u9593\uff08DoR\uff09\u70ba12.8\u500b\u6708\uff0c\u4e2d\u4f4dOS\u905417.4\u500b\u6708\u3002<\/p>\n\n\n\n

\u622a\u81f3\u76ee\u524d\uff0c\u7279\u745e\u666e\u5229\u55ae\u6297\u5df2\u5728\u4e2d\u570b\u7372\u62797\u9805\u9069\u61c9\u75c7\uff0c\u53e6\u67093\u9805\u9069\u61c9\u75c7\u7684\u4e0a\u5e02\u7533\u8acb\u6b63\u5728\u63a5\u53d7\u76e3\u7ba1\u6a5f\u69cb\u5be9\u8a55\uff1b\u5728\u570b\u969b\u4e0a\uff0c\u8a72\u7522\u54c1\u5df2\u5728\u7f8e\u570b\u7372\u62792\u9805\u9f3b\u54bd\u764c\u9069\u61c9\u75c7\uff0c\u53e6\u6709\u591a\u9805\u9069\u61c9\u75c7\u7684\u4e0a\u5e02\u7533\u8acb\u6b63\u5728\u63a5\u53d7\u6b50\u76df\u3001\u82f1\u570b\u3001\u6fb3\u5927\u5229\u4e9e\u3001\u65b0\u52a0\u5761\u76e3\u7ba1\u6a5f\u69cb\u7684\u5be9\u8a55\u3002<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u95dc\u65bc\u9f3b\u54bd\u764c<\/strong><\/p>\n\n\n\n

\u9f3b\u54bd\u764c\u662f\u4e00\u7a2e\u767c\u751f\u65bc\u9f3b\u54bd\u90e8\u9ecf\u819c\u4e0a\u76ae\u7684\u60e1\u6027\u816b\u7624\uff0c\u662f\u5e38\u898b\u7684\u982d\u9838\u90e8\u60e1\u6027\u816b\u7624\u4e4b\u4e00\u3002\u64da\u4e16\u754c\u885b\u751f\u7d44\u7e54\u7d71\u8a08\uff0c2020\u5e74\u9f3b\u54bd\u764c\u5728\u5168\u7403\u7bc4\u570d\u5167\u78ba\u8a3a\u7684\u65b0\u767c\u75c5\u4f8b\u6578\u8d85\u904e13\u842c1<\/sup>\u3002\u7531\u65bc\u539f\u767c\u816b\u7624\u4f4d\u7f6e\u7684\u539f\u56e0\uff0c\u5f88\u5c11\u63a1\u7528\u624b\u8853\u6cbb\u7642\uff0c\u91dd\u5c0d\u5c40\u9650\u6027\u764c\u75c7\u4e3b\u8981\u63a1\u7528\u653e\u7642\u6216\u653e\u5316\u7642\u7d50\u5408\u9032\u884c\u6cbb\u7642\u3002<\/p>\n\n\n\n

\u3010\u53c3\u8003\u6587\u737b\u3011<\/h5>\n\n\n\n
1. https:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/4-Nasopharynx-fact-sheet.pdf.<\/h5>\n\n\n\n

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1. \u672c\u6750\u6599\u65e8\u5728\u50b3\u905e\u524d\u6cbf\u8cc7\u8a0a\uff0c\u7121\u610f\u5411\u60a8\u505a\u4efb\u4f55\u7522\u54c1\u7684\u63a8\u5ee3\uff0c\u4e0d\u4f5c\u70ba\u81e8\u5e8a\u7528\u85e5\u6307\u5c0e\u3002<\/em><\/em><\/h6>\n\n\n\n
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